Instead of Mirth Connect
Mirth Connect alternatives
Mirth Connect is designed to move clinical information between health systems: it routes and filters messages, transforms data, and handles formats such as HL7, DICOM, EDI/X12, XML, JSON, and CSV. Its transfer choices range from MLLP and databases to SFTP, SOAP, and custom Java or JavaScript. It also offers EHR and practice-management APIs, a FHIR-enabled Patient Access API, and SMART on FHIR support. Organizations can run it themselves or use NextGen’s co-located US data centers or AWS environment.
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Make
by MakeFree plan AndroidAPIiPhone+1No-code automation across many apps — Make offers 3,000 native connectors and conditional multi-step workflows, rather than Mirth Connect’s healthcare integration focus.
Free plan Visit site - 2
Kestra
Free plan Open source APILinuxMac+3Declarative, governed cross-team workflows — Kestra adds YAML-defined flows, execution controls, and more than 2,000 plugins, while Mirth Connect centers on healthcare message integration.
Free plan Visit site - 3
Zapier
by ZapierFree plan WebConnecting a broad range of apps — Zapier offers automation across more than 9,000 apps, while Mirth Connect focuses on healthcare formats, protocols, and APIs.
Free plan · paid from $19.99/mo · 14-day trial Visit site - 4
Pabbly Connect
by Pabbly ConnectFree plan WebWeb workflow automation with refund protection — Pabbly Connect emphasizes multi-step web workflows and 2,000 native connectors, rather than Mirth Connect’s healthcare interoperability capabilities.
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Activepieces
Free plan APISelf-hostedWebTeams building workflows and AI agents — Activepieces adds chat-built flows and AI agents with governance and security controls, unlike Mirth Connect’s healthcare integration focus.
Free plan · paid from $20/mo Visit site - 6
Rayven Integration Platform
by Rayven Integration PlatformFree plan Self-hostedHybrid integration with on-premises connectors — Rayven combines hybrid deployment, on-premises connectors, and API management with workflow orchestration and data transformation.
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Integrately
by IntegratelyFree plan WebBasic web automation with a free allowance — Integrately provides web automation with 3 native connectors and a 2,000-run allowance, rather than Mirth Connect’s healthcare integration engine.
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Zoho Flow
Free plan iPhoneWeb - 9
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APIANT
Free plan APISelf-hostedWeb - 11
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Bifrost
Free plan APILinuxMac+3 - 18
Google Cloud Application Integration
Free plan APIWeb - 19 7.1 Visit site
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That healthcare focus comes with operational and licensing considerations. Customers maintain the licensed engine and build and support interfaces in-house. From version 4.6 onward, Mirth Connect uses a proprietary license, and upgrading requires a paid license; extensions are also tied to a license. Annual plan prices are available through sales, while the complimentary option is restricted to qualifying nonprofit research studies. When comparing alternatives, consider whether you need Mirth Connect’s healthcare formats and APIs or prefer broad app automation, workflow controls, or another deployment model. Also weigh platform fit, task allowances, and whether the alternative handles the systems and data you need to connect.
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