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Scan for outdated or missing drivers - takes under a minuteDriver Scan →Repair Windows errors before they cause bigger problemsFix Now →Fix the driver behind crashes, sound loss and screen glitchesFind Drivers →On average, nicotine e-cigarettes helped more adults quit smoking than nicotine replacement therapy (NRT), including patches and gum, in the evidence reviewed by Cochrane. Its 2026 summary estimates about four additional quitters per 100 people using nicotine e-cigarettes rather than NRT. That is a review-level comparison—not a prediction for any one person, device, or quit attempt—and it says nothing by itself about which option is safer.
What the updated review found
Cochrane’s living systematic review found high-certainty evidence that nicotine e-cigarettes result in more people quitting smoking than NRT. Its plain-language summary estimates that, for every 100 people trying to quit, about 8 to 10 quit with nicotine e-cigarettes, compared with about 6 using NRT. Cochrane summarizes the difference as about four more quitters per 100 people.
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These figures are averages across trial evidence, not an individual success rate. The review compares groups; it does not show that every e-cigarette, nicotine level, or way of vaping produces the same result. The evidence page says it is current to 1 January 2026, and Cochrane published its update summary on 26 August 2026. Read Cochrane’s evidence summary.
The Tool Desk
Outbyte PC Repair FREEClear out junk files and repair common Windows errorsFree Scan →Outbyte Driver Updater FREEScan for outdated or missing drivers - takes under a minuteDriver Scan →The update covered 80 randomized trials involving 29,861 participants, with nine trials new to that update. Those totals describe the review as a whole; they do not mean all 80 trials directly compared vaping with patches or gum. Cochrane’s update announcement reports the overall trial and participant counts.
#1 Best Overall
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Are patches and gum still effective?
Yes. The comparison favoring nicotine e-cigarettes does not mean patches or gum do not help people quit. Cochrane finds that licensed forms of NRT, including patches and gum, improve the chance of quitting. NRT provides nicotine without smoking; patches deliver it over time, while gum is a short-acting option.
Using more than one NRT form
A patch can be combined with a short-acting product such as gum or a lozenge. Cochrane’s review of NRT use finds combination NRT more likely to help people quit than using only one NRT form. See Cochrane’s review of ways to use NRT.
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Does the higher quit rate mean vaping is safer?
No. Quit rates measure whether people stopped smoking; they do not establish that vaping is harmless or reveal its long-term health effects. Serious unwanted effects were uncommon in the trials comparing nicotine e-cigarettes with NRT, but there were few events and uncertainty remains for several safety outcomes. The Centers for Disease Control and Prevention (CDC) says e-cigarette aerosol is not harmless and the long-term effects of vaping remain uncertain. CDC’s e-cigarette information gives its broader health guidance.
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In the United States, CDC says any potential benefit for adults who smoke and are not pregnant depends on completely replacing smoked tobacco with e-cigarettes. Using both cigarettes and e-cigarettes—often called dual use—is not an effective way to safeguard health. CDC also advises adults who use e-cigarettes to quit smoking to plan to quit vaping as well. CDC’s guidance on vaping and quitting explains these qualifications.
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What is the regulatory status in the United States?
As of CDC’s 15 May 2024 guidance, no e-cigarette product had FDA approval as a smoking-cessation aid. That is a U.S. regulatory statement, not a worldwide rule; authorization and product regulations differ by jurisdiction. Check the rules and cessation guidance where you live rather than assuming U.S. status applies elsewhere.
For U.S. adults seeking help, CDC recommends evidence-based clinical support for tobacco cessation. A health professional can help match a quit plan to a person’s circumstances, including whether an approved medication or behavioral support is appropriate. CDC’s clinical cessation guidance describes treatment approaches.
Quick Recap
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How to choose a quit-smoking approach
- If you prefer established NRT: a patch, gum, or a patch combined with gum or lozenge are supported options. Ask a clinician or pharmacist which product and use plan fit your needs.
- If considering an e-cigarette: weigh the review’s higher average quit rate against unresolved long-term safety questions and your local product rules. In the U.S., e-cigarettes are not FDA-approved cessation medicines.
- If you use an e-cigarette to stop smoking: avoid treating ongoing dual use as a health-protective endpoint. CDC’s U.S. guidance emphasizes completely replacing smoked tobacco and planning to stop vaping too.
- Whichever option you consider: add support to the plan. CDC recommends medication together with counseling; WHO points to health-professional advice, national quitlines, and mobile or digital cessation services. WHO says governments considering e-cigarettes in cessation strategies should weigh local circumstances and exhaust proven cessation strategies. WHO’s e-cigarette guidance discusses this international context.
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