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Best Electronic Lab Notebook Software in 2026

When lab work needs a digital record, compare how each notebook supports documentation, review, and later retrieval. Approval workflows, audit trails, and electronic signatures describe different parts of record handling; search scope and export formats help you assess how records can be found and taken elsewhere. API access and offline access may also matter to your working setup. LabArchives, eLabFTW, and SciNote are among the named options to consider. Check free-plan availability and paid-from pricing alongside the listed capabilities to see which details fit the way your lab manages its records.

  1. 1

    eLabFTW

    Free plan Open source APILinuxMac+3

    eLabFTW offers broad lab notebook, inventory and collaboration tools, with a free self-hosted version.

    9.0 Free plan Visit site
  2. 2

    RSpace

    Free plan Open source APILinuxMac+3

    RSpace combines notebook documentation with inventory, chemistry tools, metadata forms, and a RESTful API.

    8.6 Open source · paid from $5,000/yr Visit site
  3. 3

    SciNote

    Free plan Open source AndroidAPIiPhone+2

    SciNote brings lab records, protocol management, search, and mobile access into one platform. The one-user free tier and the staffing needs of local deployment are important constraints to weigh.

    8.5 Free plan · 14-day trial Visit site
  4. 4

    Benchling Notebook

    Free plan APIWeb

    Benchling Notebook combines experiment records, collaboration, and sample-linked results, with features Benchling says support regulated workflows.

    7.4 Free plan Visit site
  5. 5

    Chemotion ELN

    Free plan LinuxMacSelf-hosted+2

    Chemotion ELN offers chemistry-focused research records with institutional deployment and sharing options.

    7.3 Free plan Visit site
  6. 6

    LabArchives

    Free plan AndroidAPIiPhone+4

    LabArchives combines research documentation with inventory and scheduling applications, with browser and mobile-browser access.

    7.3 Free plan · paid from $330/user/yr Visit site
  7. 7

    LabCollector ELN

    Free plan AndroidAPIiPhone+5

    LabCollector ELN combines shared notebooks, configurable templates, search, and audit features, with hosting choices for different environments.

    7.3 Free plan · 30-day trial Visit site
  8. 8

    Indigo ELN

    Free plan APISelf-hostedWeb

    Indigo ELN offers chemistry-focused record management with templates, search, access controls and export options at no charge.

    7.2 Free plan Visit site
  9. 9

    Labfolder

    Free plan AndroidAPIiPhone+5

    Labfolder provides experiment documentation, team collaboration, and inventory links through a browser-based notebook.

    7.2 Free plan · 14-day trial Visit site
  10. 10

    LabID

    Free plan APISelf-hostedWeb

    LabID combines research inventory, notebook, dataset, and workflow management with export and automation options. Users outside EMBL need to deploy their own instance to use it.

    7.0 Free plan Visit site
  11. 11

    openBIS

    Free plan APILinuxSelf-hosted+1

    Choose openBIS if your research group needs an open-source system linking data, experiment notebooks, inventory, and protocols.

    6.8 Open source Visit site
  12. 12

    Sapio ELN

    Free plan APISelf-hostedWeb

    Choose Sapio ELN if your lab wants a browser-based notebook with AI assistance, molecular biology tools, data search, and collaboration features. Academic users can consider the free Bronze edition.

    6.8 Free plan · pricing on request Visit site
  13. 13

    LabKey ELN

    Free plan APISelf-hostedWeb

    LabKey ELN connects experiment records to research data and supports review and sign-off workflows.

    6.7 Free plan Visit site
  14. 14

    Phoenix ELN

    Free plan Windows

    Phoenix ELN combines protocol organization, stoichiometric details, reaction drawing, and local substructure search in an offline-capable Windows notebook.

    6.6 Free plan Visit site
  15. 15

    CDD Vault Electronic Lab Notebook

    Free trial APIWeb

    CDD Vault combines experiment documentation, assay data tools and collaboration features in a web-based research workspace.

    5.9 Pricing on request Visit site
  16. 16

    Alchemy Electronic Lab Notebook

    Paid APIWeb

    Choose Alchemy ELN if your applied sciences team needs configurable lab records, analysis charts, audit trails, and connected workflows in a browser-based system.

    5.8 Pricing on request Visit site
  17. 17

    Dotmatics Electronic Lab Notebook

    Paid APISelf-hostedWeb

    Choose Dotmatics Electronic Lab Notebook if your team needs structured scientific records, configurable experiment workflows, and search across experiment data.

    5.8 Pricing on request Visit site
  18. 18

    Signals Notebook

    Free trial APIMacWeb+1

    Signals Notebook combines experiment records, chemistry tools and team review in a cloud-based lab notebook.

    5.8 15-day trial Visit site
  19. 19

    IGOR

    Paid AndroidiPhoneWeb

    IGOR connects notebook, inventory, and team workflows, with compliance-related controls and mobile capture.

    5.6 From $30/user/mo (annual) Visit site
  20. 20

    IDBS E-WorkBook

    Paid APILinuxSelf-hosted+2

    E-WorkBook brings experimental records, lab execution, information management, and compliance features into one offering.

    5.5 Pricing on request Visit site
  21. 21

    ELabELN

    Paid AndroidiPhoneLinux+3

    ELabELN combines record controls, cross-platform access, and flexible exports in one paid product. Check that its unspecified workflow scope and unlisted price fit your needs.

  22. 22

    LabWare ELN

    Paid Web

    Choose LabWare ELN if your laboratory needs experiment records, instrument capture, and integration with LabWare LIMS or named analytical systems.

    5.1 Pricing on request Visit site
  23. 23

    BIOVIA Workbook

    Paid Windows

    BIOVIA Workbook combines traceability, electronic signatures, approval routing, broad search, and spreadsheet-friendly exports. Buyers must request pricing and verify that Windows is suitable.

    4.7 Pricing on request Visit site

#1Places #1, #2, #3, #4, #5 on this list can be bought by the makers of the software on it. See the price

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