No. 18 of 24 ·Electronic Lab Notebook Software

Signals Notebook

Web · Windows · Mac · API

Freedom report

Two barsScore 5.2

Free tierNo free tier on record
Open codeNo open-source code on record
Runs widely3 of 6 device platforms
DocumentedPlans, terms and facts published

Signals Notebook is ranked #18 of 24 in electronic lab notebook software on Freedom251. It runs on API, macOS, Web, Windows. There is no free plan. A free trial is offered.

Signals Notebook plans and pricing

All plans

Signals Notebook Standard Edition Not published Subscription includes one tenant · priced per user · automatic updates · Standard support shop.revvitysignals.com · 5 Oct 2026

Compared on electronic lab notebook software

Free plan: No
Audit trail: Yes
Electronic signatures: Yes
Approval workflows: Yes
Offline access: No
Search scope: full_text
API access: Yes
Export formats: PDF, JSON, SDF V3000, CSV, Microsoft Office, ChemDraw

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The record

Purpose: Signals Notebook is a cloud-based electronic lab notebook for capturing, organizing, and sharing R&D data across pharmaceutical, biotech, chemical, materials, and food science teams.
Experiment records: It supports flexible templates, rich text, embedded multimedia, customizable folders, tags, search, automatic versioning, and audit trails.
Chemistry: Native ChemDraw integration supports stoichiometry calculations and chemical search by CAS number, structure, or name, with PubChem safety data access.
Collaboration: Teams can share notebooks, comment, review and approve entries with electronic signatures, receive notifications, and use granular permissions.
Integrations: The product page names ChemDraw, Spotfire, Signals DLX instrument data capture, inventory management, and open APIs for LIMS, ERP, and other systems.
Security: The product page states SOC 2 certification, AWS hosting, encryption at rest and in transit, role-based permissions, and multifactor authentication.
Regulatory support: The product is described as supporting 21 CFR Part 11 requirements with electronic signatures, audit trails, and validation documentation.
Release cadence: The maker says Signals Notebook receives 10 updates per year and updates are automatic.
Trial: The maker offers a 15-day free trial; each interested user must register separately, and the trial does not include administrative functionality.
Trial content: The trial page lists preconfigured workflows, PubChem information, MS Office and PDF integrations, ChemDraw features, and experiment templates.
Access: The trial FAQ says the cloud application works in standard internet browsers including Chrome, Firefox, Safari, and Microsoft Edge, with no installation required.
Mobile support: The linked hardware and software guide says Signals is not currently qualified on mobile platforms such as phones and tablets.
Security program: The maker's security page lists SOC 2 Type 2, ISO 27001, AES-256 encryption, and automated backups every eight hours.
Support: The trial FAQ points users to in-product help resources including a Quick Start Guide, training videos, and a User Guide.

Where it ranks on Freedom251

Best Electronic Lab Notebook Software in 2026#18 of 24

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Sources

revvitysignals.com/products/research/signals-notebook-eln· checked 4 Oct 2026
cloud.info.revvitysignals.com/snb-hypertrial· checked 4 Oct 2026
revvitysignals.com/sites/default/files/2023-11/SignalsHard· checked 4 Oct 2026
revvitysignals.com/security-and-compliance· checked 4 Oct 2026
revvitysignals.com/company/about-us· checked 5 Oct 2026
shop.revvitysignals.com/product/signals-notebook-standard-editi· checked 5 Oct 2026