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Sapio ELN
What Sapio ELN is
Sapio ELN is a cloud electronic lab notebook for scientific work in biotechnology, chemistry, genetic sequencing, in vivo, bioanalytical, and clinical diagnostic settings. Its AI co-scientist, Elain, can assist with experiment planning, SOP interpretation, data analysis, visualizations, and prompt-based searches across lab data. The notebook also includes a drag-and-drop workflow builder, a configurable interface, and an English sentence rules engine.
For molecular biology, its tools cover CRISPR, plasmid and compound design, PCR primer design, Golden Gate assembly, and vector modification. Users can search structured and unstructured data, including compounds by substructure and similarity, and make scientific visualizations within the ELN. Collaboration features include real-time collaboration, experiment templates, free-form notes, instrument integration, 3D plating, and statistical calculations. The product also lists audit trails, API access, and CSV exports.
Sapio ELN is accessed in a modern web browser. Sapio offers its Bronze ELN free to academics; the Sapio ELN plan uses a tailored pricing proposal, with optional add-ons. Sapio lists SOP and GxP compliance, along with security credentials or compliance information including SOC 2 Type II, ISO 27001, HIPAA, GDPR, and HDS. The company was founded in 2004 and is headquartered in Baltimore, Maryland, United States.
Who it suits
Sapio ELN is suited to scientific teams in biotechnology, chemistry, genetic sequencing, in vivo, bioanalytical, and clinical diagnostic work. Its AI assistance, molecular biology tools, collaboration features, and configurable workflows may be useful to labs handling varied experiments and data.
What it does well
- Elain assists with experiment planning, SOPs, analysis, visualizations, and searches.
- Molecular biology tools include CRISPR and primer design.
- Search covers structured and unstructured data.
- Supports real-time collaboration, templates, and instrument integration.
- Provides API access, audit trails, and CSV exports.
- Free Bronze ELN is available for academics.
What to know first
- Sapio ELN pricing is based on a tailored proposal.
- The listed platform is web-based and requires a modern browser.
Plans
| Plan | Billed and limits | Price |
|---|---|---|
| Sapio Academic Bronze | Free for academic use only · Document search · hosted cloud · 25GB file storage · reusable experiment templates · Sapio Sheets and Docs · free-form notes · plasmid editor | Free |
| Sapio ELN | Pricing proposal tailored to your needs · Sapio Seamless ELN · charting add-on · group management · data and type designers · remote workers add-on · webhooks · optional add-ons | On request |
As sapiosciences.com lists them, read 15 Oct 2026. The maker's own page has the final word.
Getting started
- Open the Sapio ELN website in a modern web browser.
- If you are an academic, use the sign-up route for Sapio Seamless ELN Bronze.
- For the Sapio ELN plan, contact Sapio for a tailored pricing proposal.
- Choose any optional add-ons that fit your needs.
Verdict
Choose Sapio ELN if your lab wants a browser-based notebook with AI assistance, molecular biology tools, data search, and collaboration features. Academic users can consider the free Bronze edition. Teams evaluating the Sapio ELN plan should request a tailored pricing proposal and account for optional add-ons.
Questions
Is Sapio ELN free?
Sapio offers a free Bronze ELN for academics. The Sapio ELN plan is priced through a tailored proposal, with optional add-ons.
What platforms does it support?
Sapio ELN is fully cloud-based and accessed through a modern web browser.
What can Elain help with?
Elain can help plan experiments, interpret SOPs, analyze data, create visualizations, and search lab data using prompts.
Can it connect with other services?
Sapio names AWS, NVIDIA, Cadence OpenEye/Orion, CCDC, Optibrium, Schrödinger, Simulations Plus, Elsevier, SciBite, Reaxys, and DISGENET in the Elain ecosystem. The ELN also lists instrument integration and API access.
What data export and search options are listed?
The listed export format is CSV, and search covers full text and metadata. Sapio also describes searches across structured and unstructured data.
What compliance and security information does Sapio list?
The ELN page lists SOP and GxP compliance. Sapio's security information lists SOC 2 Type II, ISO 27001, HIPAA, GDPR, and HDS, and says it is certified to the EU-US, UK extension, and Swiss-US Data Privacy Frameworks.
Facts from Sapio ELN's own pages
- Acquisition news
- Axios reported on December 2, 2022 that GHO Capital acquired Sapio Sciences; deal terms were not disclosed. · axios.com, 15 Oct 2026
- AI assistance
- Elain can help design and plan experiments, interpret SOPs, analyze data, generate visualizations, and search lab data using prompts. · sapiosciences.com, 7 Oct 2026
- AI co-scientist
- Elain uses prompts to build experiments from SOP files, plan work, analyze results and search laboratory records. · sapiosciences.com, 15 Oct 2026
- API and extensibility
- Sapio exposes a RESTful API for querying and creating records and supports webhooks for integrations. · sapiosciences.com, 15 Oct 2026
- Collaboration
- Listed ELN features include real-time collaboration, experiment templates, free-form notes, instrument integration, 3D plating, and built-in statistical calculations. · sapiosciences.com, 7 Oct 2026
- Company founded
- LinkedIn lists Sapio Sciences as founded in 2004. · linkedin.com, 15 Oct 2026
- Company headquarters and size
- LinkedIn lists headquarters in Baltimore, Maryland and company size of 51–200 employees. · linkedin.com, 15 Oct 2026
- Company legal name
- Crunchbase lists the legal name as Sapio Sciences, LLC. · crunchbase.com, 15 Oct 2026
- Compliance
- The ELN page lists SOP and GxP compliance; Sapio’s security page lists SOC 2 Type II, ISO 27001, HIPAA, GDPR, and HDS credentials or compliance information. · sapiosciences.com, 7 Oct 2026
- Data analysis
- Sapio says users can search structured and unstructured data, including compounds by substructure and similarity, and create scientific visualizations within the ELN. · sapiosciences.com, 7 Oct 2026
- Deployment
- The free-ELN page says the product is cloud-based with no installation, while also describing cloud or on-premise data access options. · sapiosciences.com, 15 Oct 2026
- Documentation and support
- Sapio advertises a support forum, resource library, customer support by email or phone and implementation help. · sapiosciences.com, 15 Oct 2026
- Experiment collaboration
- Listed ELN capabilities include reusable experiment templates, free-form notes and real-time collaboration. · g2.com, 15 Oct 2026
- Flow cytometry
- Sapio Flow ELN supports FCS drag-and-drop, histograms, machine-learning QC, automated and manual gating, compensation matrices and shared gating strategies. · sapiosciences.com, 15 Oct 2026
- Founded
- 2004 · sapiosciences.com, 28 Sept 2026
- Free edition
- Sapio says its Bronze ELN is free for academics and provides a sign-up link for Sapio Seamless ELN Bronze. · sapiosciences.com, 7 Oct 2026
- GxP positioning
- Sapio markets templated GxP-compliant solutions for research, diagnostics and manufacturing workflows. · sapiosciences.com, 15 Oct 2026
- Headquarters
- Baltimore, Maryland, United States · sapiosciences.com, 28 Sept 2026
- Independent coverage
- FitGap reports Sapio ELN covers 55 of 90 evaluated ELN requirements across biology, chemistry, LIMS-integrated and GxP categories. · us.fitgap.com, 15 Oct 2026
- Independent praise
- Scispot's review identifies workflow flexibility, automation, scientific-data access, multi-use-case support, sample management and AI as recurring positive themes. · scispot.com, 15 Oct 2026
- Independent pricing limit
- Scispot reports that Sapio does not publish a standard enterprise price and instead uses tailored proposals with optional add-ons. · scispot.com, 15 Oct 2026
- Instrument integration
- The integration framework offers predefined instrument configurations, customizable setups, Rules Engine triggers, File Bridge and RESTful API connections. · sapiosciences.com, 15 Oct 2026
- Integrations
- Sapio’s Elain ecosystem names AWS, NVIDIA, Cadence OpenEye/Orion, CCDC, Optibrium, Schrödinger, Simulations Plus, Elsevier, SciBite, Reaxys, and DISGENET. · sapiosciences.com, 7 Oct 2026
- Intended users
- Sapio describes ELN use cases across biotechnology, chemistry, genetic sequencing, in vivo, bioanalytical, and clinical diagnostic work. · sapiosciences.com, 7 Oct 2026
Where Sapio ELN stands on Freedom251
- Electronic Lab Notebook Software#12 of 23