Axelium is a platform for systematic reviews and meta-analyses, taking work from evidence search through reporting and living reviews. Its 11-stage workflow includes protocol planning, screening, full-text review, data extraction, RoB 2.0, GRADE, statistics and network meta-analysis. The maker says AI extracts structured values, while deterministic analysis code calculates statistics; extracted data points link to snippets in original PDFs. Listed methods include pairwise and network synthesis, GRADE certainty ratings, CERQual and PRISMA-style reporting. Users can import references from tools such as EndNote, Zotero and Mendeley, and from sources including PubMed, ClinicalTrials.gov and Web of Science. Exports include Word, Excel, RIS, BibTeX and RevMan. Team controls include reviewer roles, comments, dual-person sign-off and audit snapshots. Axelium is available as a web product and browser extension. The Free plan provides one lifetime review and one seat; Researcher costs $29/mo. Human validation is needed for screening suggestions, extracted values, risk-of-bias assessments and generated reports. Recurring statistical refresh for living-review network meta-analysis is paused.
Who it is for
Axelium suits individual researchers, pharma and HEOR teams, CROs, consultancies, HTA bodies and clinical guideline committees. Teams needing shared review roles and sign-offs may use its collaboration controls.
What is good
- 11 stages span search through reporting.
- Data points link to source PDF snippets.
- Supports pairwise and network synthesis.
- Free plan includes one lifetime review.
- Imports references from named tools and databases.
What to know first
- Screening suggestions need reviewer validation.
- Extracted values and risk assessments need checking.
- Generated reports are drafts requiring review.
- Recurring living-review NMA refresh is paused.
Verdict
Axelium brings review workflows, analysis methods and collaboration controls into one platform. Its free plan is limited to one lifetime review, and reviewers still need to validate AI-assisted outputs.
Axelium plans and pricing
All plansCompared on AI literature review software
- Free plan
- Yes
- Paid from
- $29/mo
- Screening workflow
- Yes
- AI paper summaries
- Yes
- Full-text analysis
- Yes
- Systematic review support
- Yes
- Collaboration seats
- 1
- Export formats
- DOCX, XLSX, RIS, BibTeX, RevMan





