GENOME is an amp modeler, effects suite, and virtual cabinet engine for guitar and bass. Its CODEX engine loads Neural Amp Modeler (NAM), AIDA-X, and Proteus captures in one workflow, and the product page says it includes more than 40 premium AI amp captures. Users can create series or parallel signal paths with up to 12 components per lane and expand to two lanes. GENOME runs as a standalone app or as VST3, AU, and AAX plugins; the maker lists Pro Tools, Logic Pro X, Ableton Live, Cubase, Studio One, and Reaper as tested DAWs. Parameter automation, MIDI mapping, and MIDI Learn support external hardware control. The free GENOME Intro plan includes 4 TSM-Ai amplifiers, 14 pedals, 5 DynIR cabinets, and 4 Studio FX. The GENOME license costs 89.99 USD per once and includes 24 amps, 49 pedals, 16 DynIR cabinets, and 16 Studio FX, but excludes FairTone and Artist Series premium components. A 14-day free trial is available. A Two notes account is required to use GENOME.
Who it is for
GENOME suits guitarists and bassists who want amp modeling, effects, and cabinet tools in a standalone app or plugin. It is available for macOS, Windows, and iPad, though desktop licensing does not include GENOME iOS.
What is good
- Loads NAM, AIDA-X, and Proteus captures.
- Supports series and parallel routing with dual-lane expansion.
- Runs standalone or as VST3, AU, and AAX plugins.
- Free Intro plan includes amps, pedals, cabinets, and Studio FX.
- Offers a 14-day free trial.
What to know first
- A Two notes account is required.
- Desktop GENOME license does not include GENOME iOS.
- GENOME costs 89.99 USD per once.
- GENOME Suite excludes FairTone and Artist Series components.
Verdict
GENOME combines amp and cabinet modeling with effects, routing, and plugin support. Check the component exclusions and the separate iOS access requirement when choosing a license.
GENOME plans and pricing
All plansCompared on guitar amp software
- Free plan
- Yes
- Amp models
- 24 models
- Cabinet models
- 16 models
- Effects count
- 65 effects
- Plugin formats
- VST3, AU, AAX
- Standalone app
- Yes
- IR loader
- Yes
- Supported platforms
- macOS, Windows



