No. 25 of 25 ·Research Project Management Software

Advarra OnCore

Web · API

Freedom report

One barScore 4.9

Free tierNo free tier on record
Open codeNo open-source code on record
Runs widely1 of 6 device platforms
DocumentedPlans, terms and facts published

Advarra OnCore is ranked #25 of 25 in research project management software on Freedom251. It runs on API, Web. There is no free plan.

Advarra OnCore plans and pricing

All plans

OnCore CTMS Not published Annual subscription; fee depends on licensed modules and protocol volume. Additional modules, such as biospecimen management, are licensed separately advarra.com · 4 Oct 2026

Compared on research project management software

Protocol management: Yes
Milestone tracking: Yes
Deployment options: cloud

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The record

Purpose: OnCore is a clinical trial management system for managing clinical research operations across a trial’s lifecycle.
Intended users: Advarra says OnCore typically serves academic medical centers, cancer centers, and some health systems conducting 50 to 500+ active trials.
Research and finance workflows: The system supports clinical research management, protocol and participant workflows, budgeting, invoicing, receivables, and billing compliance.
EMR integrations: OnCore connects with Epic and Cerner and supports exchange of subject, protocol, demographic, and billing data with EMR systems.
Other integrations: Listed integrations include eIRB through the OnCore API, EMR billing grids and demographics, general ledger, OnCore Analytics, and Advarra Payments.
Specialized modules: Additional capabilities include biospecimen management, protocol review management, registry management, and Advarra EDC technology for investigator-initiated trials.
Analytics: OnCore Analytics provides visualizations and insights related to accrual, study activation, staff effort, and other clinical trial operations.
Cancer center reporting: Advarra describes support for NCI reporting, internal auditing, data safety oversight, automated data table reporting, and PRMC workflows.
Security and compliance: Advarra Cloud is described as meeting SOC 2, HIPAA, 21 CFR Part 11, and NIST 800-53 standards.
Hosting and support: Advarra describes its cloud platform as SaaS hosted on AWS, with cloud technology experts providing system management and support.
Pricing detail: The annual subscription covers license, maintenance, support, and upgrades; Advarra directs prospective customers to sales for pricing.
Company history: Advarra says it took its current shape in 2017 when Schulman IRB and Chesapeake IRB came together to form the company.
Headquarters: Columbia, Maryland, United States

Where it ranks on Freedom251

Best Research Project Management Software in 2026#25 of 25
Best Research Administration Software in 2026#18 of 20

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Sources

advarra.com/solutions/sites/ctms/oncore/· checked 4 Oct 2026
advarra.com/info-sheet/advarra-cloud/· checked 4 Oct 2026
advarra.com/about/· checked 4 Oct 2026