Freedom251 › Clinical Trial Management
Advarra OnCore
What Advarra OnCore is
Advarra OnCore is a clinical trial management system for coordinating clinical research operations from study setup through a trial’s lifecycle. Its workflows cover protocols and participants as well as budgeting, invoicing, receivables, and billing compliance. Advarra says it typically serves academic medical centers, cancer centers, and some health systems conducting 50 to 500 or more active trials.
OnCore exchanges subject, protocol, demographic, and billing data with Epic and Cerner EMR systems. Other listed connections include eIRB through the OnCore API, EMR billing grids and demographics, general ledger, OnCore Analytics, and Advarra Payments. Optional modules cover biospecimen, protocol review, and registry management, with Advarra EDC technology for investigator-initiated trials. Analytics visualizes accrual, study activation, staff effort, and other operations. Cancer-center workflows include NCI reporting, internal audits, data safety oversight, automated data tables, and PRMC processes. The cloud service runs on AWS. Advarra says its cloud platform meets SOC 2, HIPAA, 21 CFR Part 11, and NIST 800-53 standards.
Who it suits
OnCore suits academic medical centers, cancer centers, and health systems managing substantial clinical trial portfolios. Its research and financial workflows may also suit organizations that need to coordinate trial administration and billing.
What it does well
- Supports protocol and participant workflows.
- Connects with Epic and Cerner EMR systems.
- Analytics covers accrual and study activation.
- Cloud platform is described as meeting named compliance standards.
What to know first
- No free plan is listed.
- Pricing is available on request.
- Additional modules are licensed separately.
Limits
There is no free plan. The annual subscription fee depends on licensed modules and protocol volume, and additional modules such as biospecimen management are licensed separately.
Plans
| Plan | Billed and limits | Price |
|---|---|---|
| OnCore CTMS | Annual subscription; fee depends on licensed modules and protocol volume. · Additional modules, such as biospecimen management, are licensed separately | On request |
As advarra.com lists them, read 4 Oct 2026. The maker's own page has the final word.
Getting started
- Visit the OnCore product website.
- Contact Advarra sales for pricing.
- Discuss the annual subscription and licensed modules.
- Use the cloud deployment.
Verdict
OnCore brings clinical research operations and financial workflows together, with integrations and specialized modules for larger research programs. Pricing depends on licensed modules and protocol volume, and prospective customers must request a quote.
Questions
How much does OnCore cost?
Pricing is on request. The annual subscription covers license, maintenance, support, and upgrades; its fee depends on licensed modules and protocol volume.
Is there a free plan?
No, the pricing information identifies OnCore as paid with no free plan.
Which platforms are supported?
The listed platforms are web and API. Deployment is cloud.
Which EMR systems does OnCore connect with?
It connects with Epic and Cerner and supports exchange of subject, protocol, demographic, and billing data.
What integrations are listed?
They include eIRB through the OnCore API, EMR billing grids and demographics, general ledger, OnCore Analytics, and Advarra Payments.
What security standards does Advarra Cloud meet?
Advarra describes the cloud platform as meeting SOC 2, HIPAA, 21 CFR Part 11, and NIST 800-53 standards.
Facts from Advarra OnCore's own pages
- Analytics
- OnCore Analytics provides visualizations and insights related to accrual, study activation, staff effort, and other clinical trial operations. · advarra.com, 4 Oct 2026
- Cancer center reporting
- Advarra describes support for NCI reporting, internal auditing, data safety oversight, automated data table reporting, and PRMC workflows. · advarra.com, 4 Oct 2026
- Company history
- Advarra says it took its current shape in 2017 when Schulman IRB and Chesapeake IRB came together to form the company. · advarra.com, 4 Oct 2026
- EMR integrations
- OnCore connects with Epic and Cerner and supports exchange of subject, protocol, demographic, and billing data with EMR systems. · advarra.com, 4 Oct 2026
- Headquarters
- Columbia, Maryland, United States · advarra.com, 28 Sept 2026
- Hosting and support
- Advarra describes its cloud platform as SaaS hosted on AWS, with cloud technology experts providing system management and support. · advarra.com, 4 Oct 2026
- Intended users
- Advarra says OnCore typically serves academic medical centers, cancer centers, and some health systems conducting 50 to 500+ active trials. · advarra.com, 4 Oct 2026
- Other integrations
- Listed integrations include eIRB through the OnCore API, EMR billing grids and demographics, general ledger, OnCore Analytics, and Advarra Payments. · advarra.com, 4 Oct 2026
- Pricing detail
- The annual subscription covers license, maintenance, support, and upgrades; Advarra directs prospective customers to sales for pricing. · advarra.com, 4 Oct 2026
- Purpose
- OnCore is a clinical trial management system for managing clinical research operations across a trial’s lifecycle. · advarra.com, 4 Oct 2026
- Research and finance workflows
- The system supports clinical research management, protocol and participant workflows, budgeting, invoicing, receivables, and billing compliance. · advarra.com, 4 Oct 2026
- Security and compliance
- Advarra Cloud is described as meeting SOC 2, HIPAA, 21 CFR Part 11, and NIST 800-53 standards. · advarra.com, 4 Oct 2026
- Specialized modules
- Additional capabilities include biospecimen management, protocol review management, registry management, and Advarra EDC technology for investigator-initiated trials. · advarra.com, 4 Oct 2026
Where Advarra OnCore stands on Freedom251
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