Best oxDNA Alternatives in 2026
Updated
20 apps from physics simulation software ranked against oxDNA on the same published basis.
- 1oxDNA vs OpenSim
- 2oxDNA vs Xcos
- 3oxDNA vs SimFlow
- 4oxDNA vs FeenoX
- 5oxDNA vs FEST-3D
- 6oxDNA vs FDTDX
- 7oxDNA vs DynamicalSystems.jl
- 8oxDNA vs myPhysicsLab
- 9oxDNA vs Open Source Physics
- 10oxDNA vs PhysSandbox
- 11oxDNA vs 3JCN Physics Simulation
- 12oxDNA vs SimScale
- 13oxDNA vs PhysicsPlayground
- 14oxDNA vs COMSOL Multiphysics
- 15oxDNA vs OpenFOAM
- 16oxDNA vs Ansys Fluent
- 17oxDNA vs Chombo-Discharge
- 18oxDNA vs ngspice
- 19oxDNA vs Physion
- 20oxDNA vs Step
oxDNA alternatives compared
| # | App | Score | Free plan | From | Runs on |
|---|---|---|---|---|---|
| 1 | OpenSim | 8.0 | Free plan | Free | API, Linux, Mac, Windows |
| 2 | Xcos | 7.9 | Free plan | Free | Windows, Mac, Linux |
| 3 | SimFlow | 7.9 | Free plan | €666.67/mo | Linux, Mac, Web, Windows |
| 4 | FeenoX | 7.8 | Free plan | Free | API, Linux, self-hosted, Web |
| 5 | FEST-3D | 7.7 | Free plan | Free | Linux, Mac |
| 6 | FDTDX | 7.6 | Free plan | Free | Linux, self-hosted |
| 7 | DynamicalSystems.jl | 7.6 | Free plan | Free | Linux, Mac, Windows |
| 8 | myPhysicsLab | 7.6 | Free plan | Free | Linux, Mac, self-hosted, Web, Windows |
| 9 | Open Source Physics | 7.1 | No | — | Web, Windows, Mac, Linux, iOS, Android |
| 10 | PhysSandbox | 7.1 | Free plan | Free | Web |
| 11 | 3JCN Physics Simulation | 7.1 | Free plan | Free | Web |
| 12 | SimScale | 7.0 | No | — | Web |
| 13 | PhysicsPlayground | 7.0 | Free plan | Free | Web |
| 14 | COMSOL Multiphysics | 6.9 | No | — | API, Linux, Mac, self-hosted, Web, Windows |
| 15 | OpenFOAM | 6.9 | No | — | Windows, Mac, Linux |
| 16 | Ansys Fluent | 6.8 | No | — | — |
| 17 | Chombo-Discharge | 6.8 | Free plan | Free | Linux |
| 18 | ngspice | 6.7 | No | — | Windows, Mac, Linux |
| 19 | Physion | 6.7 | Free plan | $6/mo | Web |
| 20 | Step | 6.6 | No | — | Linux |
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Questions about oxDNA alternatives
What is the best alternative to oxDNA?
OpenSim, number 1 in physics simulation software with a score of 8.0 out of 10. The others here: Xcos, SimFlow, FeenoX and 16 more.
What is the best free alternative to oxDNA?
OpenSim is the best-ranked alternative with a free plan. 13 of the 20 alternatives here publish a free plan on their own pricing pages.
How are these alternatives ranked?
Ranked free-and-open first: a usable free tier and open-source code, then the platforms it runs on and its documentation.